De Panne (French: La Panne) is a town and a municipality located on the North Sea coast of the Belgian province of West Flanders. There it borders France, which implies that it is the westernmost location of Belgium.
The municipality comprises apart from De Panne the village of Adinkerke.
On 1 January 2006 De Panne had a total population of 10,060 on a total area of 23.90 km², which gives a population density of 421 inhabitants per km².